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Fluoxetine reverses the memory impairment and reduction in proliferation and survival of hippocampal cells caused by methotrexate chemotherapy
RATIONALE: Adjuvant cancer chemotherapy can cause long-lasting, cognitive deficits. It is postulated that these impairments are due to these drugs targeting neural precursors within the adult hippocampus, the loss of which has been associated with memory impairment. OBJECTIVES: The present study inv...
Autores principales: | Lyons, Laura, ElBeltagy, Maha, Umka, Jariya, Markwick, Rachel, Startin, Carla, Bennett, Geoffrey, Wigmore, Peter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072503/ https://www.ncbi.nlm.nih.gov/pubmed/21181126 http://dx.doi.org/10.1007/s00213-010-2122-2 |
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