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Rotigotine Effects on Early Morning Motor Function and Sleep in Parkinson's Disease: A Double-Blind, Randomized, pLacebo-Controlled Study (RECOVER)

In a multinational, double-blind, placebo-controlled trial (NCT00474058), 287 subjects with Parkinson's disease (PD) and unsatisfactory early-morning motor symptom control were randomized 2:1 to receive rotigotine (2–16 mg/24 hr [n = 190]) or placebo (n = 97). Treatment was titrated to optimal...

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Detalles Bibliográficos
Autores principales: Trenkwalder, Claudia, Kies, Bryan, Rudzinska, Monika, Fine, Jennifer, Nikl, Janos, Honczarenko, Krystyna, Dioszeghy, Peter, Hill, Dennis, Anderson, Tim, Myllyla, Vilho, Kassubek, Jan, Steiger, Malcolm, Zucconi, Marco, Tolosa, Eduardo, Poewe, Werner, Surmann, Erwin, Whitesides, John, Boroojerdi, Babak, Chaudhuri, Kallol Ray
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072524/
https://www.ncbi.nlm.nih.gov/pubmed/21322021
http://dx.doi.org/10.1002/mds.23441