Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment

Inhibitors of proteasomes have been shown to affect endocytosis of multiple membrane receptors, in particular at the step of cargo sorting for lysosomal degradation. Here we demonstrate that the inhibition of proteasomes causes specific redistribution of an endosomal adaptor APPL1, which undergoes i...

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Detalles Bibliográficos
Autores principales: Pilecka, Iwona, Sadowski, Lukasz, Kalaidzidis, Yannis, Miaczynska, Marta
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072527/
https://www.ncbi.nlm.nih.gov/pubmed/21320486
http://dx.doi.org/10.1016/j.yexcr.2011.02.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072527/
https://www.ncbi.nlm.nih.gov/pubmed/21320486
http://dx.doi.org/10.1016/j.yexcr.2011.02.002

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