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Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment
Inhibitors of proteasomes have been shown to affect endocytosis of multiple membrane receptors, in particular at the step of cargo sorting for lysosomal degradation. Here we demonstrate that the inhibition of proteasomes causes specific redistribution of an endosomal adaptor APPL1, which undergoes i...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072527/ https://www.ncbi.nlm.nih.gov/pubmed/21320486 http://dx.doi.org/10.1016/j.yexcr.2011.02.002 |