Ibudilast, a Pharmacologic Phosphodiesterase Inhibitor, Prevents Human Immunodeficiency Virus-1 Tat-Mediated Activation of Microglial Cells

Human Immunodeficiency Virus-1 (HIV-1)-associated neurocognitive disorders (HAND) occur, in part, due to the inflammatory response to viral proteins, such as the HIV-1 transactivator of transcription (Tat), in the central nervous system (CNS). Given the need for novel adjunctive therapies for HAND,...

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Detalles Bibliográficos
Autores principales: Kiebala, Michelle, Maggirwar, Sanjay B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072977/
https://www.ncbi.nlm.nih.gov/pubmed/21494611
http://dx.doi.org/10.1371/journal.pone.0018633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072977/
https://www.ncbi.nlm.nih.gov/pubmed/21494611
http://dx.doi.org/10.1371/journal.pone.0018633

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