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Methylation and Loss of Secreted Frizzled-Related Protein 3 Enhances Melanoma Cell Migration and Invasion

BACKGROUND: Wnt signaling is important in development and can also contribute to the initiation and progression of cancer. The Secreted Frizzled Related Proteins (SFRPs) constitute a family of Wnt modulators, crucial for controlling Wnt signaling. Here we investigate the expression and role of SFRP3...

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Detalles Bibliográficos
Autores principales: Ekström, Elin J., Sherwood, Victoria, Andersson, Tommy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072980/
https://www.ncbi.nlm.nih.gov/pubmed/21494614
http://dx.doi.org/10.1371/journal.pone.0018674