Cargando…

Antibody-Mediated “Universal” Osteoclast Targeting Platform using Calcitonin as a Model Drug

PURPOSE: To generate and characterize a specific monoclonal antibody (mAb) against recombinant human RANK receptor and to develop an antiresorptive strategy using this mAb as an osteoclast-targeting platform that selectively targets osteoclast cells whilst delivering an attached (i.e. chemically con...

Descripción completa

Detalles Bibliográficos
Autores principales: Newa, Madhuri, Bhandari, Krishna Hari, Tang, Lili, Kalvapalle, Rohit, Suresh, Mavanur, Doschak, Michael R.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073043/
https://www.ncbi.nlm.nih.gov/pubmed/21301934
http://dx.doi.org/10.1007/s11095-011-0376-y