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Antibody-Mediated “Universal” Osteoclast Targeting Platform using Calcitonin as a Model Drug
PURPOSE: To generate and characterize a specific monoclonal antibody (mAb) against recombinant human RANK receptor and to develop an antiresorptive strategy using this mAb as an osteoclast-targeting platform that selectively targets osteoclast cells whilst delivering an attached (i.e. chemically con...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073043/ https://www.ncbi.nlm.nih.gov/pubmed/21301934 http://dx.doi.org/10.1007/s11095-011-0376-y |