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LC–MS–MS Method for the Analysis of New Non-Imidazole Histamine H(3) Receptor Antagonist 1-[3-(4-tert-Butylphenoxy)propyl]piperidine in Rat Serum—Application to Pharmacokinetic Studies

A sensitive and specific liquid chromatography electrospray ionisation–tandem mass spectrometry method for determination of new non-imidazole histamine H(3) receptor antagonist 1-[3-(4-tert-butylphenoxy)propyl]piperidine (DL76) in rat serum has been developed and validated. Chromatography was perfor...

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Detalles Bibliográficos
Autores principales: Szafarz, Malgorzata, Szymura-Oleksiak, Joanna, Lazewska, Dorota, Kiec-Kononowicz, Katarzyna
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073091/
https://www.ncbi.nlm.nih.gov/pubmed/21544189
http://dx.doi.org/10.1007/s10337-011-1983-9