Signaling Diversity of PKA Achieved Via a Ca(2+)-cAMP-PKA Oscillatory Circuit

Many protein kinases are key nodal signaling molecules that regulate a wide range of cellular functions. These functions may require complex spatiotemporal regulation of kinase activities. Here, we show that Protein Kinase A (PKA), Ca(2+) and cAMP oscillate in sync in insulin-secreting MIN6 β cells,...

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Detalles Bibliográficos
Autores principales: Ni, Qiang, Ganesan, Ambhighainath, Aye-Han, Nwe-Nwe, Gao, Xinxin, Allen, Michael D., Levchenko, Andre, Zhang, Jin
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073414/
https://www.ncbi.nlm.nih.gov/pubmed/21102470
http://dx.doi.org/10.1038/nchembio.478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073414/
https://www.ncbi.nlm.nih.gov/pubmed/21102470
http://dx.doi.org/10.1038/nchembio.478

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