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Signaling Diversity of PKA Achieved Via a Ca(2+)-cAMP-PKA Oscillatory Circuit
Many protein kinases are key nodal signaling molecules that regulate a wide range of cellular functions. These functions may require complex spatiotemporal regulation of kinase activities. Here, we show that Protein Kinase A (PKA), Ca(2+) and cAMP oscillate in sync in insulin-secreting MIN6 β cells,...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073414/ https://www.ncbi.nlm.nih.gov/pubmed/21102470 http://dx.doi.org/10.1038/nchembio.478 |