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The cilia protein IFT88 is required for spindle orientation in mitosis

Cilia dysfunction has long been associated with cyst formation and ciliopathies1. More recently, misoriented cell division has been observed in cystic kidneys2, but the molecular mechanism leading to this abnormality remains unclear. Proteins of the intraflagellar transport (IFT) machinery are linke...

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Detalles Bibliográficos
Autores principales: Delaval, Benedicte, Bright, Alison, Lawson, Nathan, Doxsey, Stephen
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073523/
https://www.ncbi.nlm.nih.gov/pubmed/21441926
http://dx.doi.org/10.1038/ncb2202