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Impairment of brain endothelial glucose transporter by methamphetamine causes blood-brain barrier dysfunction

BACKGROUND: Methamphetamine (METH), an addictive psycho-stimulant drug with euphoric effect is known to cause neurotoxicity due to oxidative stress, dopamine accumulation and glial cell activation. Here we hypothesized that METH-induced interference of glucose uptake and transport at the endothelium...

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Detalles Bibliográficos
Autores principales: Abdul Muneer, P M, Alikunju, Saleena, Szlachetka, Adam M, Murrin, L Charles, Haorah, James
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073895/
https://www.ncbi.nlm.nih.gov/pubmed/21426580
http://dx.doi.org/10.1186/1750-1326-6-23