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Matrix metalloproteinase-9 predicts pulmonary status declines in α(1)-antitrypsin deficiency

BACKGROUND: Matrix metalloproteinase-9 (MMP-9) may be important in the progression of emphysema, but there have been few longitudinal clinical studies of MMP-9 including pulmonary status and COPD exacerbation outcomes. METHODS: We utilized data from the placebo arm (n = 126) of a clinical trial of p...

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Detalles Bibliográficos
Autores principales: Omachi, Theodore A, Eisner, Mark D, Rames, Alexis, Markovtsova, Lada, Blanc, Paul D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073899/
https://www.ncbi.nlm.nih.gov/pubmed/21429222
http://dx.doi.org/10.1186/1465-9921-12-35