Long term culture of mesenchymal stem cells in hypoxia promotes a genetic program maintaining their undifferentiated and multipotent status

BACKGROUND: In the bone marrow, hematopietic and mesenchymal stem cells form a unique niche in which the oxygen tension is low. Hypoxia may have a role in maintaining stem cell fate, self renewal and multipotency. However, whereas most studies addressed the effect of transient in vitro exposure of M...

Descripción completa

Detalles Bibliográficos
Autores principales: Basciano, Leticia, Nemos, Christophe, Foliguet, Bernard, de Isla, Natalia, de Carvalho, Marcelo, Tran, Nguyen, Dalloul, Ali
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073900/
https://www.ncbi.nlm.nih.gov/pubmed/21450070
http://dx.doi.org/10.1186/1471-2121-12-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073900/
https://www.ncbi.nlm.nih.gov/pubmed/21450070
http://dx.doi.org/10.1186/1471-2121-12-12

Ejemplares similares