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FGFR2 protein expression in breast cancer: nuclear localisation and correlation with patient genotype

BACKGROUND: Single Nucleotide Polymorphisms (SNPs) in intron 2 of the Fibroblast Growth Factor Receptor Type 2 (FGFR2) gene, including rs2981582, contribute to multifactorial breast cancer susceptibility. The high risk polymorphism haplotype in the FGFR2 gene has been associated with increased mRNA...

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Detalles Bibliográficos
Autores principales: Martin, Amy J, Grant, Andrew, Ashfield, Alison M, Palmer, Colin N, Baker, Lee, Quinlan, Philip R, Purdie, Colin A, Thompson, Alastair M, Jordan, Lee B, Berg, Jonathan N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073906/
https://www.ncbi.nlm.nih.gov/pubmed/21418638
http://dx.doi.org/10.1186/1756-0500-4-72