Cargando…

FGFR2 protein expression in breast cancer: nuclear localisation and correlation with patient genotype

BACKGROUND: Single Nucleotide Polymorphisms (SNPs) in intron 2 of the Fibroblast Growth Factor Receptor Type 2 (FGFR2) gene, including rs2981582, contribute to multifactorial breast cancer susceptibility. The high risk polymorphism haplotype in the FGFR2 gene has been associated with increased mRNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martin, Amy J, Grant, Andrew, Ashfield, Alison M, Palmer, Colin N, Baker, Lee, Quinlan, Philip R, Purdie, Colin A, Thompson, Alastair M, Jordan, Lee B, Berg, Jonathan N
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073906/ https://www.ncbi.nlm.nih.gov/pubmed/21418638 http://dx.doi.org/10.1186/1756-0500-4-72

Ejemplares similares

An integrated informatics platform to facilitate transforming tissue into knowledge
por: Quinlan, PR, et al.
Publicado: (2010)

Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP
por: Quinlan, Philip R., et al.
Publicado: (2022)

The Informatics Challenges Facing Biobanks: A Perspective from a United Kingdom Biobanking Network
por: Quinlan, Philip R., et al.
Publicado: (2015)

Prospective comparison of switches in biomarker status between primary and recurrent breast cancer: the Breast Recurrence In Tissues Study (BRITS)
por: Thompson, Alastair M, et al.
Publicado: (2010)

MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism
por: Paulin, Fiona EM, et al.
Publicado: (2008)

Progesterone receptor expression is an independent prognostic variable in early breast cancer: a population-based study
por: Purdie, C A, et al.
Publicado: (2014)

Immunohistochemical detection of Polo-like kinase-1 (PLK1) in primary breast cancer is associated with TP53 mutation and poor clinical outcome
por: King, Sharon I, et al.
Publicado: (2012)

The RNA helicase p68 modulates expression and function of the Δ133 isoform(s) of p53, and is inversely associated with Δ133p53 expression in breast cancer
por: Moore, Hayley C, et al.
Publicado: (2010)

Increased mortality in HER2 positive, oestrogen receptor positive invasive breast cancer: a population-based study
por: Purdie, C A, et al.
Publicado: (2010)

Quantitative shear wave ultrasound elastography: initial experience in solid breast masses
por: Evans, Andrew, et al.
Publicado: (2010)

Comparing computer-generated and pathologist-generated tumour segmentations for immunohistochemical scoring of breast tissue microarrays
por: Akbar, Shazia, et al.
Publicado: (2015)

p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients
por: Bourdon, Jean-Christophe, et al.
Publicado: (2011)

Histological evaluation of AMPK signalling in primary breast cancer
por: Hadad, Sirwan M, et al.
Publicado: (2009)

p53 mutation, deprivation and poor prognosis in primary breast cancer
por: Baker, L, et al.
Publicado: (2010)

Etoposide Induces Nuclear Re-Localisation of AID
por: Lambert, Laurens J., et al.
Publicado: (2013)

A prospective comparison of ER, PR, Ki67 and gene expression in paired sequential core biopsies of primary, untreated breast cancer
por: Hadad, Sirwan M., et al.
Publicado: (2016)

∆Np63/p40 correlates with the location and phenotype of basal/mesenchymal cancer stem‐like cells in human ER(+) and HER2(+) breast cancers
por: Liu, Yajing, et al.
Publicado: (2019)

Structural characterisation of TNRC6A nuclear localisation signal in complex with importin-alpha
por: Chaston, Jessica J., et al.
Publicado: (2017)

Does shear wave ultrasound independently predict axillary lymph node metastasis in women with invasive breast cancer?
por: Evans, Andrew, et al.
Publicado: (2013)

Pre-operative stromal stiffness measured by shear wave elastography is independently associated with breast cancer-specific survival
por: Evans, Andy, et al.
Publicado: (2018)

Localised Peritonitis
por: Baker, C. O.
Publicado: (1896)

Spatial localisation in autism: evidence for differences in early cortical visual processing
por: Latham, Keziah, et al.
Publicado: (2013)

Adenovirus Terminal Protein Contains a Bipartite Nuclear Localisation Signal Essential for Its Import into the Nucleus
por: Al-Wassiti, Hareth A., et al.
Publicado: (2021)

Localised release of matrix metallopeptidase 8 in fatal cerebral malaria
por: Georgiadou, Athina, et al.
Publicado: (2021)

Expression profiling of nuclear receptors in breast cancer identifies TLX as a mediator of growth and invasion in triple-negative breast cancer
por: Lin, Meng-Lay, et al.
Publicado: (2015)

Age as an independent prognostic factor for survival of localised synovial sarcoma patients
por: Vlenterie, Myrella, et al.
Publicado: (2015)

Detection and localisation of unilateral hindlimb pathologies in cattle using the cow pedogram
por: Alsaaod, Maher, et al.
Publicado: (2019)

Caudal Fgfr1 disruption produces localised spinal mis-patterning and a terminal myelocystocele-like phenotype in mice
por: Maniou, Eirini, et al.
Publicado: (2023)

Smart-aggregation imaging for single molecule localisation with SPAD cameras
por: Gyongy, Istvan, et al.
Publicado: (2016)

The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer
por: Shah, R, et al.
Publicado: (2009)

Interim heterogeneity changes measured using entropy texture features on T2-weighted MRI at 3.0 T are associated with pathological response to neoadjuvant chemotherapy in primary breast cancer
por: Henderson, Shelley, et al.
Publicado: (2017)

Are baseline ultrasound and mammographic features associated with rates of pathological completes response in patients receiving neoadjuvant chemotherapy for breast cancer?
por: Savaridas, Sarah L., et al.
Publicado: (2019)

Nuclear localisation of nuclear factor-kappaB transcription factors in prostate cancer: an immunohistochemical study
por: Lessard, L, et al.
Publicado: (2005)

Multiparameter DNA content analysis identifies distinct groups in primary breast cancer
por: Dayal, J H S, et al.
Publicado: (2013)

Joint association of polymorphism of the FGFR4 gene and mutation TP53 gene with bladder cancer prognosis
por: Yang, Y C, et al.
Publicado: (2006)

Absence of amplification of the FGFR1-gene in human malignant mesothelioma of the pleura: a pilot study
por: Plönes, Till, et al.
Publicado: (2014)

Co-localisation and secretion of glucagon-like peptide 1 and peptide YY from primary cultured human L cells
por: Habib, A. M., et al.
Publicado: (2013)

Subcellular localisation of FLAG tagged enzymes of the dynamic protein S-palmitoylation cycle of Trypanosoma cruzi epimastigotes
por: Batista, Cassiano Martin, et al.
Publicado: (2018)

Treatment with FGFR2-IIIc monoclonal antibody suppresses weight gain and adiposity in KKA(y) mice
por: Nonogaki, K, et al.
Publicado: (2016)

Membrane-Associated, Not Cytoplasmic or Nuclear, FGFR1 Induces Neuronal Differentiation
por: Csanaky, Katalin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ogaf596u38ldbj4r0aqdl2rrt2