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Induction of Plasmodium falciparum-Specific CD4(+) T Cells and Memory B Cells in Gabonese Children Vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D)

The recombinant circumsporozoite protein (CS) based vaccine, RTS,S, confers protection against Plasmodium falciparum infection in controlled challenge trials and in field studies. The RTS,S recombinant antigen has been formulated with two adjuvant systems, AS01 and AS02, which have both been shown t...

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Detalles Bibliográficos
Autores principales: Agnandji, Selidji T., Fendel, Rolf, Mestré, Michaël, Janssens, Michel, Vekemans, Johan, Held, Jana, Gnansounou, Ferdinand, Haertle, Sonja, von Glasenapp, Isabel, Oyakhirome, Sunny, Mewono, Ludovic, Moris, Philippe, Lievens, Marc, Demoitie, Marie-Ange, Dubois, Patrice M., Villafana, Tonya, Jongert, Erik, Olivier, Aurelie, Cohen, Joe, Esen, Meral, Kremsner, Peter G., Lell, Bertrand, Mordmüller, Benjamin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073948/
https://www.ncbi.nlm.nih.gov/pubmed/21494604
http://dx.doi.org/10.1371/journal.pone.0018559