A Model of a MAPK•Substrate Complex in an Active Conformation: A Computational and Experimental Approach

The mechanisms by which MAP kinases recognize and phosphorylate substrates are not completely understood. Efforts to understand the mechanisms have been compromised by the lack of MAPK-substrate structures. While MAPK-substrate docking is well established as a viable mechanism for bringing MAPKs and...

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Detalles Bibliográficos
Autores principales: Lee, Sunbae, Warthaka, Mangalika, Yan, Chunli, Kaoud, Tamer S., Piserchio, Andrea, Ghose, Ranajeet, Ren, Pengyu, Dalby, Kevin N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073974/
https://www.ncbi.nlm.nih.gov/pubmed/21494553
http://dx.doi.org/10.1371/journal.pone.0018594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073974/
https://www.ncbi.nlm.nih.gov/pubmed/21494553
http://dx.doi.org/10.1371/journal.pone.0018594

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