Somatic coding mutations in human induced pluripotent stem cells

Defined transcription factors can induce epigenetic reprogramming of adult mammalian cells into induced pluripotent stem cells. Although DNA factors are integrated during some reprogramming methods, it is unknown whether the genome remains unchanged at the single nucleotide level. Here we show that...

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Detalles Bibliográficos
Autores principales: Gore, Athurva, Li, Zhe, Fung, Ho-Lim, Young, Jessica, Agarwal, Suneet, Antosiewicz-Bourget, Jessica, Canto, Isabel, Giorgetti, Alessandra, Israel, Mason, Kiskinis, Evangelos, Lee, Je-Hyuk, Loh, Yuin-Han, Manos, Philip D., Montserrat, Nuria, Panopoulos, Athanasia D., Ruiz, Sergio, Wilbert, Melissa, Yu, Junying, Kirkness, Ewen F., Belmonte, Juan Carlos Izpisua, Rossi, Derrick J., Thomson, James, Eggan, Kevin, Daley, George Q., Goldstein, Lawrence S.B., Zhang, Kun
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074107/
https://www.ncbi.nlm.nih.gov/pubmed/21368825
http://dx.doi.org/10.1038/nature09805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074107/
https://www.ncbi.nlm.nih.gov/pubmed/21368825
http://dx.doi.org/10.1038/nature09805

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