Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae

EndA is a sequence non-specific endonuclease that serves as a virulence factor during Streptococcus pneumoniae infection. Expression of EndA provides a strategy for evasion of the host's neutrophil extracellular traps, digesting the DNA scaffold structure and allowing further invasion by S. pne...

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Detalles Bibliográficos
Autores principales: Moon, Andrea F., Midon, Marika, Meiss, Gregor, Pingoud, Alfred, London, Robert E., Pedersen, Lars C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074123/
https://www.ncbi.nlm.nih.gov/pubmed/21113026
http://dx.doi.org/10.1093/nar/gkq1152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074123/
https://www.ncbi.nlm.nih.gov/pubmed/21113026
http://dx.doi.org/10.1093/nar/gkq1152

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