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Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae

EndA is a sequence non-specific endonuclease that serves as a virulence factor during Streptococcus pneumoniae infection. Expression of EndA provides a strategy for evasion of the host's neutrophil extracellular traps, digesting the DNA scaffold structure and allowing further invasion by S. pne...

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Detalles Bibliográficos
Autores principales:	Moon, Andrea F., Midon, Marika, Meiss, Gregor, Pingoud, Alfred, London, Robert E., Pedersen, Lars C.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074123/ https://www.ncbi.nlm.nih.gov/pubmed/21113026 http://dx.doi.org/10.1093/nar/gkq1152

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