Evolution of eukaryal tRNA-guanine transglycosylase: insight gained from the heterocyclic substrate recognition by the wild-type and mutant human and Escherichia coli tRNA-guanine transglycosylases

The enzyme tRNA-guanine transglycosylase (TGT) is involved in the queuosine modification of tRNAs in eukarya and eubacteria and in the archaeosine modification of tRNAs in archaea. However, the different classes of TGTs utilize different heterocyclic substrates (and tRNA in the case of archaea). Bas...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Chen, Brooks, Allen F., Goodenough-Lashua, DeeAnne M., Kittendorf, Jeffrey D., Showalter, Hollis D., Garcia, George A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074131/
https://www.ncbi.nlm.nih.gov/pubmed/21131277
http://dx.doi.org/10.1093/nar/gkq1188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074131/
https://www.ncbi.nlm.nih.gov/pubmed/21131277
http://dx.doi.org/10.1093/nar/gkq1188

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