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USP7/HAUSP stimulates repair of oxidative DNA lesions

USP7 is involved in the cellular stress response by regulating Mdm2 and p53 protein levels following severe DNA damage. In addition to this, USP7 may also play a role in chromatin remodelling by direct deubiquitylation of histones, as well as indirectly by regulating the cellular levels of E3 ubiqui...

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Detalles Bibliográficos
Autores principales: Khoronenkova, Svetlana V., Dianova, Irina I., Parsons, Jason L., Dianov, Grigory L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074138/
https://www.ncbi.nlm.nih.gov/pubmed/21138959
http://dx.doi.org/10.1093/nar/gkq1210