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Replication fork stalling by bulky DNA damage: localization at active origins and checkpoint modulation
The integrity of the genome is threatened by DNA damage that blocks the progression of replication forks. Little is known about the genomic locations of replication fork stalling, and its determinants and consequences in vivo. Here we show that bulky DNA damaging agents induce localized fork stallin...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074140/ https://www.ncbi.nlm.nih.gov/pubmed/21138968 http://dx.doi.org/10.1093/nar/gkq1215 |