Engineering cooperative tecto–RNA complexes having programmable stoichiometries

High affinity and specificity RNA–RNA binding interfaces can be constructed by combining pairs of GNRA loop/loop–receptor interaction motifs. These interactions can be fused using flexible four-way junction motifs to create divalent, self-assembling scaffolding units (‘tecto-RNA’) that have favorabl...

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Detalles Bibliográficos
Autores principales: Novikova, Irina V., Hassan, Bachar H., Mirzoyan, Marina G., Leontis, Neocles B.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074147/
https://www.ncbi.nlm.nih.gov/pubmed/21138969
http://dx.doi.org/10.1093/nar/gkq1231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074147/
https://www.ncbi.nlm.nih.gov/pubmed/21138969
http://dx.doi.org/10.1093/nar/gkq1231

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