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CHILD: a new tool for detecting low-abundance insertions and deletions in standard sequence traces
Several methods have been proposed for detecting insertion/deletions (indels) from chromatograms generated by Sanger sequencing. However, most such methods are unsuitable when the mutated and normal variants occur at unequal ratios, such as is expected to be the case in cancer, with organellar DNA o...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074157/ https://www.ncbi.nlm.nih.gov/pubmed/21278161 http://dx.doi.org/10.1093/nar/gkq1354 |