Biochemical behavior of N-oxidized cytosine and adenine bases in DNA polymerase-mediated primer extension reactions

To clarify the biochemical behavior of 2′-deoxyribonucleoside 5′-triphosphates and oligodeoxyribonucleotides (ODNs) containing cytosine N-oxide (C(o)) and adenine N-oxide (A(o)), we examined their base recognition ability in DNA duplex formation using melting temperature (T(m)) experiments and their...

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Detalles Bibliográficos
Autores principales: Tsunoda, Hirosuke, Kudo, Tomomi, Masaki, Yoshiaki, Ohkubo, Akihiro, Seio, Kohji, Sekine, Mitsuo
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074161/
https://www.ncbi.nlm.nih.gov/pubmed/21300642
http://dx.doi.org/10.1093/nar/gkq914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074161/
https://www.ncbi.nlm.nih.gov/pubmed/21300642
http://dx.doi.org/10.1093/nar/gkq914

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