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Biochemical behavior of N-oxidized cytosine and adenine bases in DNA polymerase-mediated primer extension reactions

To clarify the biochemical behavior of 2′-deoxyribonucleoside 5′-triphosphates and oligodeoxyribonucleotides (ODNs) containing cytosine N-oxide (C(o)) and adenine N-oxide (A(o)), we examined their base recognition ability in DNA duplex formation using melting temperature (T(m)) experiments and their...

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Detalles Bibliográficos
Autores principales:	Tsunoda, Hirosuke, Kudo, Tomomi, Masaki, Yoshiaki, Ohkubo, Akihiro, Seio, Kohji, Sekine, Mitsuo
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Synthetic Biology and Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074161/ https://www.ncbi.nlm.nih.gov/pubmed/21300642 http://dx.doi.org/10.1093/nar/gkq914

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