Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing

MicroRNAs (miRNAs) are prevalent regulatory RNAs that mediate gene silencing and play key roles in diverse cellular processes. While synthetic RNA-based regulatory systems that integrate regulatory and sensing functions have been demonstrated, the lack of detail on miRNA structure–function relations...

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Detalles Bibliográficos
Autores principales: Beisel, Chase L., Chen, Yvonne Y., Culler, Stephanie J., Hoff, Kevin G., Smolke, Christina D.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074164/
https://www.ncbi.nlm.nih.gov/pubmed/21149259
http://dx.doi.org/10.1093/nar/gkq954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074164/
https://www.ncbi.nlm.nih.gov/pubmed/21149259
http://dx.doi.org/10.1093/nar/gkq954

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