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Interpreting protein/DNA interactions: distinguishing specific from non-specific and electrostatic from non-electrostatic components

We discuss the effectiveness of existing methods for understanding the forces driving the formation of specific protein–DNA complexes. Theoretical approaches using the Poisson–Boltzmann (PB) equation to analyse interactions between these highly charged macromolecules to form known structures are con...

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Detalles Bibliográficos
Autores principales: Privalov, Peter L., Dragan, Anatoly I., Crane-Robinson, Colyn
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074165/
https://www.ncbi.nlm.nih.gov/pubmed/21071403
http://dx.doi.org/10.1093/nar/gkq984