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Interpreting protein/DNA interactions: distinguishing specific from non-specific and electrostatic from non-electrostatic components
We discuss the effectiveness of existing methods for understanding the forces driving the formation of specific protein–DNA complexes. Theoretical approaches using the Poisson–Boltzmann (PB) equation to analyse interactions between these highly charged macromolecules to form known structures are con...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074165/ https://www.ncbi.nlm.nih.gov/pubmed/21071403 http://dx.doi.org/10.1093/nar/gkq984 |