Structure and Function of an Irreversible Agonist-β(2) Adrenoceptor complex

G protein-coupled receptors (GPCRs) are eukaryotic integral membrane proteins that modulate biological function by initiating cellular signaling in response to chemically diverse agonists. Despite recent progress in the structural biology of GPCRs1, the molecular basis for agonist binding and allost...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosenbaum, Daniel M., Zhang, Cheng, Lyons, Joseph, Holl, Ralph, Aragao, David, Arlow, Daniel H., Rasmussen, Søren G. F., Choi, Hee-Jung, DeVree, Brian T., Sunahara, Roger K., Chae, Pil Seok, Gellman, Samuel H., Dror, Ron O., Shaw, David E., Weis, William I., Caffrey, Martin, Gmeiner, Peter, Kobilka, Brian K.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074335/
https://www.ncbi.nlm.nih.gov/pubmed/21228876
http://dx.doi.org/10.1038/nature09665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074335/
https://www.ncbi.nlm.nih.gov/pubmed/21228876
http://dx.doi.org/10.1038/nature09665

Ejemplares similares