Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer

BACKGROUND: Thromboxane synthase (TXS) metabolises prostaglandin H2 into thromboxanes, which are biologically active on cancer cells. TXS over-expression has been reported in a range of cancers, and associated with a poor prognosis. TXS inhibition induces cell death in-vitro, providing a rationale f...

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Detalles Bibliográficos
Autores principales: Cathcart, Mary-Clare, Gately, Kathy, Cummins, Robert, Kay, Elaine, O'Byrne, Kenneth J, Pidgeon, Graham P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074522/
https://www.ncbi.nlm.nih.gov/pubmed/21388528
http://dx.doi.org/10.1186/1476-4598-10-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074522/
https://www.ncbi.nlm.nih.gov/pubmed/21388528
http://dx.doi.org/10.1186/1476-4598-10-25

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