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Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer
BACKGROUND: Thromboxane synthase (TXS) metabolises prostaglandin H2 into thromboxanes, which are biologically active on cancer cells. TXS over-expression has been reported in a range of cancers, and associated with a poor prognosis. TXS inhibition induces cell death in-vitro, providing a rationale f...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074522/ https://www.ncbi.nlm.nih.gov/pubmed/21388528 http://dx.doi.org/10.1186/1476-4598-10-25 |