Gene amplification in human cells knocked down for RAD54

BACKGROUND: In mammalian cells gene amplification is a common manifestation of genome instability promoted by DNA double-strand breaks (DSBs). The repair of DSBs mainly occurs through two mechanisms: non-homologous end-joining (NHEJ) and homologous recombination (HR). We previously showed that defec...

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Detalles Bibliográficos
Autores principales: Ruiz-Herrera, Aurora, Smirnova, Alexandra, Khouriauli, Lela, Nergadze, Solomon G, Mondello, Chiara, Giulotto, Elena
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074559/
https://www.ncbi.nlm.nih.gov/pubmed/21418575
http://dx.doi.org/10.1186/2041-9414-2-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074559/
https://www.ncbi.nlm.nih.gov/pubmed/21418575
http://dx.doi.org/10.1186/2041-9414-2-5

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