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NMR Analysis Demonstrates Immunoglobulin G N-glycans are Accessible and Dynamic
The N-glycan at Asn297 of the Immunoglobulin G Fc fragment modulates cellular responses of the adaptive immune system. However, the underlying mechanism remains undefined as existing structural data suggest the glycan does not directly engage cell surface receptors. Here we characterize the dynamics...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074608/ https://www.ncbi.nlm.nih.gov/pubmed/21258329 http://dx.doi.org/10.1038/nchembio.511 |