A stimulatory TSH receptor antibody enhances adipogenesis via phosphoinositide 3-kinase activation in orbital preadipocytes from patients with Graves' ophthalmopathy

Graves' ophthalmopathy (GO) is characterized by expanded volume of the orbital tissues associated with elevated serum levels of TSH receptor (TSHR) autoantibodies. Because previous studies have demonstrated evidence of adipogenesis within the GO orbit, we sought to determine whether M22, a huma...

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Detalles Bibliográficos
Autores principales: Kumar, Seema, Nadeem, Sarah, Stan, Marius N, Coenen, Michael, Bahn, Rebecca S
Formato: Texto
Lenguaje:English
Publicado: Society for Endocrinology 2011
Materias:
Regular Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074639/
https://www.ncbi.nlm.nih.gov/pubmed/21321093
http://dx.doi.org/10.1530/JME-11-0006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074639/
https://www.ncbi.nlm.nih.gov/pubmed/21321093
http://dx.doi.org/10.1530/JME-11-0006

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