Members of the Histone H3 Lysine 4 Trimethylation Complex Regulate Lifespan in a Germline-dependent Manner in C. elegans

The plasticity of aging suggests that longevity may be controlled epigenetically by specific alterations in chromatin state. The link between chromatin and aging has mostly focused on histone deacetylation by the Sir2 family1,2, but less is known about the role of other histone modifications in long...

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Detalles Bibliográficos
Autores principales: Greer, Eric L., Maures, Travis J., Hauswirth, Anna G., Green, Erin M., Leeman, Dena S., Maro, Géraldine S., Han, Shuo, Banko, Max R., Gozani, Or, Brunet, Anne
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075006/
https://www.ncbi.nlm.nih.gov/pubmed/20555324
http://dx.doi.org/10.1038/nature09195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075006/
https://www.ncbi.nlm.nih.gov/pubmed/20555324
http://dx.doi.org/10.1038/nature09195

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