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Dynamic Analysis of Stochastic Transcription Cycles

In individual mammalian cells the expression of some genes such as prolactin is highly variable over time and has been suggested to occur in stochastic pulses. To investigate the origins of this behavior and to understand its functional relevance, we quantitatively analyzed this variability using ne...

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Detalles Bibliográficos
Autores principales: Harper, Claire V., Finkenstädt, Bärbel, Woodcock, Dan J., Friedrichsen, Sönke, Semprini, Sabrina, Ashall, Louise, Spiller, David G., Mullins, John J., Rand, David A., Davis, Julian R. E., White, Michael R. H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075210/
https://www.ncbi.nlm.nih.gov/pubmed/21532732
http://dx.doi.org/10.1371/journal.pbio.1000607