Cargando…
Dynamic Analysis of Stochastic Transcription Cycles
In individual mammalian cells the expression of some genes such as prolactin is highly variable over time and has been suggested to occur in stochastic pulses. To investigate the origins of this behavior and to understand its functional relevance, we quantitatively analyzed this variability using ne...
Autores principales: | Harper, Claire V., Finkenstädt, Bärbel, Woodcock, Dan J., Friedrichsen, Sönke, Semprini, Sabrina, Ashall, Louise, Spiller, David G., Mullins, John J., Rand, David A., Davis, Julian R. E., White, Michael R. H. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075210/ https://www.ncbi.nlm.nih.gov/pubmed/21532732 http://dx.doi.org/10.1371/journal.pbio.1000607 |
Ejemplares similares
-
A stochastic transcriptional switch model for single cell imaging data
por: Hey, Kirsty L., et al.
Publicado: (2015) -
Transcription Factor Pit-1 Affects Transcriptional Timing in the Dual-Promoter Human Prolactin Gene
por: McNamara, Anne V, et al.
Publicado: (2021) -
Multiplexing information flow through dynamic signalling systems
por: Minas, Giorgos, et al.
Publicado: (2020) -
Asymmetry between Activation and Deactivation during a Transcriptional Pulse
por: Dunham, Lee S.S., et al.
Publicado: (2017) -
A hierarchical model of transcriptional dynamics allows robust estimation of transcription rates in populations of single cells with variable gene copy number
por: Woodcock, Dan J., et al.
Publicado: (2013)