Evaluation of Multidrug Efflux Pump Inhibitors by a New Method Using Microfluidic Channels

Fluorescein-di-β-d-galactopyranoside (FDG), a fluorogenic compound, is hydrolyzed by β-galactosidase in the cytoplasm of Escherichia coli to produce a fluorescent dye, fluorescein. We found that both FDG and fluorescein were substrates of efflux pumps, and have developed a new method to evaluate eff...

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Detalles Bibliográficos
Autores principales: Matsumoto, Yoshimi, Hayama, Kohei, Sakakihara, Shouichi, Nishino, Kunihiko, Noji, Hiroyuki, Iino, Ryota, Yamaguchi, Akihito
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075257/
https://www.ncbi.nlm.nih.gov/pubmed/21533264
http://dx.doi.org/10.1371/journal.pone.0018547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075257/
https://www.ncbi.nlm.nih.gov/pubmed/21533264
http://dx.doi.org/10.1371/journal.pone.0018547

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