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Evaluation of Multidrug Efflux Pump Inhibitors by a New Method Using Microfluidic Channels
Fluorescein-di-β-d-galactopyranoside (FDG), a fluorogenic compound, is hydrolyzed by β-galactosidase in the cytoplasm of Escherichia coli to produce a fluorescent dye, fluorescein. We found that both FDG and fluorescein were substrates of efflux pumps, and have developed a new method to evaluate eff...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075257/ https://www.ncbi.nlm.nih.gov/pubmed/21533264 http://dx.doi.org/10.1371/journal.pone.0018547 |