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Efficacious and Safe Tissue-Selective Controlled Gene Therapy Approaches for the Cornea

Untargeted and uncontrolled gene delivery is a major cause of gene therapy failure. This study aimed to define efficient and safe tissue-selective targeted gene therapy approaches for delivering genes into keratocytes of the cornea in vivo using a normal or diseased rabbit model. New Zealand White r...

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Detalles Bibliográficos
Autores principales: Mohan, Rajiv R., Sinha, Sunilima, Tandon, Ashish, Gupta, Rangan, Tovey, Jonathan C. K., Sharma, Ajay
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075266/
https://www.ncbi.nlm.nih.gov/pubmed/21533273
http://dx.doi.org/10.1371/journal.pone.0018771