Cargando…

Calcineurin Signaling and Membrane Lipid Homeostasis Regulates Iron Mediated MultiDrug Resistance Mechanisms in Candida albicans

We previously demonstrated that iron deprivation enhances drug susceptibility of Candida albicans by increasing membrane fluidity which correlated with the lower expression of ERG11 transcript and ergosterol levels. The iron restriction dependent membrane perturbations led to an increase in passive...

Descripción completa

Detalles Bibliográficos
Autores principales: Hameed, Saif, Dhamgaye, Sanjiveeni, Singh, Ashutosh, Goswami, Shyamal K., Prasad, Rajendra
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075269/
https://www.ncbi.nlm.nih.gov/pubmed/21533276
http://dx.doi.org/10.1371/journal.pone.0018684