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p53 regulates epithelial-mesenchymal transition (EMT) and stem cell properties through modulating miRNAs
Epithelial mechenchymal transition (EMT) has recently been linked to stem cell phenotype1, 2. However, the molecular mechanism involving regulation of EMT and stemness remains elusive. Here, using genomic approaches, we discovered that tumor suppressor p53 plays a role in regulating both EMT and EMT...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075845/ https://www.ncbi.nlm.nih.gov/pubmed/21336307 http://dx.doi.org/10.1038/ncb2173 |