p53 regulates epithelial-mesenchymal transition (EMT) and stem cell properties through modulating miRNAs

Epithelial mechenchymal transition (EMT) has recently been linked to stem cell phenotype1, 2. However, the molecular mechanism involving regulation of EMT and stemness remains elusive. Here, using genomic approaches, we discovered that tumor suppressor p53 plays a role in regulating both EMT and EMT...

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Detalles Bibliográficos
Autores principales: Chang, Chun-Ju, Chao, Chi-Hong, Xia, Weiya, Yang, Jer-Yen, Xiong, Yan, Li, Chia-Wei, Yu, Wen-Hsuan, Rehman, Sumaiyah K., Hsu, Jennifer L., Lee, Heng-Huan, Liu, Mo, Chen, Chun-Te, Yu, Dihua, Hung, Mien-Chie
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075845/
https://www.ncbi.nlm.nih.gov/pubmed/21336307
http://dx.doi.org/10.1038/ncb2173

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