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Thermoreversible Pluronic(®) F127-based hydrogel containing liposomes for the controlled delivery of paclitaxel: in vitro drug release, cell cytotoxicity, and uptake studies
PURPOSE: To develop an in situ gel system comprising liposome-containing paclitaxel (PTX) dispersed within the thermoreversible gel (Pluronic(®) F127 gel) for controlled release and improved antitumor drug efficiency. METHODS: The dialysis membrane and membrane-less diffusion method were used to inv...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075891/ https://www.ncbi.nlm.nih.gov/pubmed/21499415 http://dx.doi.org/10.2147/IJN.S15057 |