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Thermoreversible Pluronic(®) F127-based hydrogel containing liposomes for the controlled delivery of paclitaxel: in vitro drug release, cell cytotoxicity, and uptake studies

PURPOSE: To develop an in situ gel system comprising liposome-containing paclitaxel (PTX) dispersed within the thermoreversible gel (Pluronic(®) F127 gel) for controlled release and improved antitumor drug efficiency. METHODS: The dialysis membrane and membrane-less diffusion method were used to inv...

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Detalles Bibliográficos
Autores principales: Nie, Shufang, Hsiao, WL Wendy, Pan, Weisan, Yang, Zhijun
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075891/
https://www.ncbi.nlm.nih.gov/pubmed/21499415
http://dx.doi.org/10.2147/IJN.S15057