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Brain delivery of valproic acid via intranasal administration of nanostructured lipid carriers: in vivo pharmacodynamic studies using rat electroshock model

The treatment of brain disorders is one of the greatest challenges in drug delivery because of a variety of main barriers in effective drug transport and maintaining therapeutic concentrations in the brain for a prolonged period. The objective of this study was delivery of valproic acid (VPA) to the...

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Detalles Bibliográficos
Autores principales: Eskandari, Sharareh, Varshosaz, Jaleh, Minaiyan, Mohsen, Tabbakhian, Majid
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075902/
https://www.ncbi.nlm.nih.gov/pubmed/21499426
http://dx.doi.org/10.2147/IJN.S15881