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TNFR2 interposes the proliferative and NF-κB-mediated inflammatory response by podocytes to TNF-α

The development of proliferative podocytopathies has been linked to ligation of TNFR2 expressed on the renal parenchyma; however, the TNFR2 positive cells within the kidney responsible for podocyte injury are unknown. We detected de novo expression of TNFR2 on podocytes prior to hyperplastic injury...

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Detalles Bibliográficos
Autores principales: Bruggeman, Leslie A., Drawz, Paul E., Kahoud, Nicole, Lin, Ke, Barisoni, Laura, Nelson, Peter J.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075956/
https://www.ncbi.nlm.nih.gov/pubmed/21221075
http://dx.doi.org/10.1038/labinvest.2010.199